Jodi Nunnari
Professor
Molecular and Cellular Biology (College of Biological Sciences)
0214A Briggs Hall
Office 530.754.9774
Lab
jmnunnari@ucdavis.edu
Degrees:
1989 - PhD - Vanderbilt University - Pharmacology
1984 - BA - College of Wooster, Ohio - Chemistry
Awards:
Chancellor's Fellow
Phi Beta Kappa
Professional Societies:
The American Society for Cell Biology
American Society for Biochemistry and Molecular Biology
Grad Group Affiliations and Specialties:
Biochemistry and Molecular Biology
Cell and Developmental Biology
Microbiology
Publications:
Cassidy-Stone, A., Chipuk, J.E., Ingerman, E., Song, C., Yoo, C., Kuwana, T., Kurth, M.J., Shaw. J., Hinshaw. J.E., Green, D.R., and Nunnari, J. 2008 Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak dependent mitochondrial outer membrane permeabilization. Developmental Cell, in press.
Meeusen S, DeVay R, Block J, Cassidy-Stone A, Wayson S, McCaffery JM, Nunnari J. Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1. Cell. 2006 Oct 20;127(2):383-95.
Hoppins, S., Lackner, L. and Nunnari, J. 2007 The machines that fuse and divide mitochondria. Annual Review of Biochemistry, 76: 751-80.
Naylor K, Ingerman E, Okreglak V, Marino M, Hinshaw JE, Nunnari J. Mdv1 interacts with assembled dnm1 to promote mitochondrial division. J Biol Chem. 2006 Jan 27;281(4):2177-83. Epub 2005 Nov 4.
Ingerman E, Nunnari J. A continuous, regenerative coupled GTPase assay for dynamin-related proteins. Methods Enzymol. 2005;404:611-9.
Ingerman E, Perkins EM, Marino M, Mears JA, McCaffery JM, Hinshaw JE, Nunnari J. Dnm1 forms spirals that are structurally tailored to fit mitochondria. J Cell Biol. 2005 Sep 26;170(7):1021-7.
Meeusen, S., McCaffrey, J.M., and Nunnari, J. (2004) Mitochondrial fusion intermediates revealed in vitro. Science, in press and published online at Science Express, 5 August 2004 / Page 1/ 10.1126/science.1100612.
Osteryoung, K and Nunnari J. (2003) The division of endosymbiotic organelles. Science, 302: 1698-1704.
Meeusen, S. and Nunnari, J. (2003) Evidence for a two membrane-spanning autonomous mitochondrial DNA replisome. Journal of Cell Biology, 63: 503-510.
Scott, S.V., Cassidy-Stone, A. Meeusen, S.L. and Nunnari, J. (2003) Staying in aerobic shape: How the structural integrity of mitochondria and mtDNA is maintained. Current Opinion in Cell Biology, 15:482-8.
Wong, E.D., Wagner J.A., Scott, S.V., Okreglak, V., Holewinske, T.J., Cassidy-Stone, A., and Nunnari, J. (2003) The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion. Journal of Cell Biology, 160, 303-311.
Tieu, Q., Okreglak, V., Naylor, K., and Nunnari, J. (2002) The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission. Journal of Cell Biology, 158, 445-452.
Nunnari, J., Wong, E., Meeusen, S., and Wagner, J. (2002) Methods for studying the behavior of mitochondria. In Guide to Yeast Genetics and Molecular and Cell Biology, Methods in Enzymology, vol. 30, Guthrie and Fink.
Nunnari, J. and Shaw J.M. Mitochondrial dynamics and division in budding yeast. (2002) Trends in Cell Biology, 12:178-84.
Tieu, Q. and Nunnari, J. . 2000. Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division. Journal of Cell Biology. 151:353-365
Wong, E.D., Wagner J.A., Gorsich, S., McCaffery, J.M., Shaw, J.M., and Nunnari, J.. 2000. The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria. Journal of Cell Biology. 151:341-352
Meeusen, S., Tieu, Q., Wong, E., Weiss, E., Schieltz, D., Yates, J.R. and Nunnari, J. . (1999) Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA. Journal of Cell Biology 145, 291-304.
Research Interests:
My laboratory is interested in the mechanisms that govern the organization and transmission of mitochondria and mitochondrial DNA in eukaryotic cells.
![[Picture of Jodi Nunnari]](/FacultyProfiles/Common/PersonalImages/1344.jpg)
